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Sunday sees the initial Wear-Tyne derby after 2024, but who will emerge victorious – the Black Cats or the Magpies?
"Throughout the majority of last season, no one would have predicted Sunderland getting promoted and being competitive with Eddie Howe's Newcastle, let alone being above them in the table," commented analyst Chris Sutton.
"It is very different now, and the way Sunderland play convinces me they've got a genuine opportunity."
Sutton is making predictions for all 380 Premier League games this campaign, in competition with artificial intelligence, readers and a range of guests.
For week 16, he faces off against England Gaming star Daniel 'Stingray' Ray.
Ray is vying for victory for the national gaming squad – the Football Association's recognised esports team – at the gaming title Uefa eEuro 2025 finals tournament, which will occur at Twickenham Stadium on Saturday.
Viewers can catch Uefa's YouTube, Instagram Live and short-form video channels, as well as EA Sports FC Twitch and YouTube and the national team's Twitch.
Do you agree with their forecasts? You can make your own projections below.
The most commonly selected scoreline picked for each game is used in the scoreboards at the end of this page.
Getting the win/draw/loss right (picking a win, draw or defeat) is worth 10 points. A perfect prediction earns forty points.
Ray, who represents Gen City and the Premier League champions as well as England, is entering the fray at the eEuros finals after getting through the qualification rounds.
The final eight competitors will fly the flag at the finals in a straight knockout, vying for a substantial cash prize and a coveted spot in the FC Pro World Championship Play-Ins, with Denmark's Anders Vejrgang looking to retain the title he won last year.
"My mindset is really good for it," Ray stated. "I've got a really good coach with me and training has been going well.
"Representing your country is always an honour to play for your country. Naturally when you are younger, you fantasise about doing it as an real-life footballer, but when you enter this field and there is an chance to represent England, donning the national jersey is something special.
"I defeated Vejrgang 9-4 in qualifying to get here. I've played against him over the course of the season just in practice, and in other tournaments before - but I'd never beaten him in a tournament before.
"For me he is the best player in the world so beating him in a tournament like this just delivers a massive injection of confidence."
Premier League Forecasts
Saturday, 13 December
Chelsea vs Everton
Stamford Bridge, 15:00 GMT
Chelsea were outstanding against the Gunners at the end of November, when they got a draw after going down to 10 men, and it seemed they've turned a corner, they could potentially be challengers for the crown.
In the matches following, however, they were overpowered by Leeds, looked uninspired against Bournemouth and this week got beaten by Atalanta in the Champions League.
So manager Enzo Maresca really needs a win here to restore momentum, but it won't be easy because the Toffees are such a dangerous team.
Their key midfielders are playing exceptionally and they have got a bit of form at the moment.
Based on recent performances you would likely back the visitors, while the most logical prediction would likely be a draw, but I'm throwing caution to the wind.
Chelsea haven't given me any real reason to back them recently, but I just have a gut instinct Chelsea will win this match because they are at home and they are due a win.
Sutton's prediction: 2-1
Stingray's prediction: With this being at the Bridge, I am going to back Chelsea. I think they will start off really well and go 2-0 up, then Everton will nick one back but then Chelsea score late. 3-1
AI's prediction: 2-0
Liverpool vs Brighton
Anfield, 15:00 GMT
I am at this game and it will be intriguing to see what we get from Liverpool.
I was delighted for Reds boss Arne Slot to get such a important victory at Inter Milan on Tuesday following all the stuff with Mohamed Salah this week.
Slot shouldn't need to put up with that drama. I know Salah has been a legend for the club but at its core Slot just wants to win games and there is nothing personal in his team selection.
Liverpool changed their tactical setup against Inter and went with a midfield diamond formation and two up top.
All the talk is going to be talking about whether Salah is selected for this game, but the only way he is going to be brought back into the fold is if he makes amends.
Slot's focus will be on winning this game, but it is a tough one.
You could argue it is the same for most teams but I find Brighton so hard to predict. I always feel they have got a goal in them, but they are vulnerable at the back too.
The Merseysiders need to get back to a consistent run of form, but I am not sure how much their efforts at the San Siro will have drained them.
I've selected a couple of Brighton players in my Fantasy Premier League side, so they will probably lose now - but I do fancy get something at Anfield.
Sutton's prediction: 2-2
Stingray's prediction: This is a game which is going to give Liverpool a bit more of their confidence back. Obviously they had a good win in midweek and they can build more momentum here. 2-1
AI's prediction: 3-1
Sunday, 14 December
Sunderland vs Newcastle
Stadium of Light, 14:00 GMT
The Black Cats have had the opportunity to rest while Newcastle had to battle intensely against Bayer Leverkusen on Wednesday, only to concede a late equaliser late on.
Aside from their brilliant performance against Everton a couple of weeks ago, Newcastle's away form has been poor, particularly straight after they've played in the Champions League.
It is anticipated that that tendency to continue on Sunday, and their fatigue is likely to be a key element in how this game goes because of their rivals' high press.
It was evident how unwavering Regis le Bris's side are. They dominated the Gunners, and it was incredible to watch.
Everyone talks about how Granit Xhaka has been outstanding for the Black Cats, and he has been brilliant, but Noah Sadiki, who plays in midfield with him, has also been one of the signings of the season and warrants praise too.
All signs point to this being the best game|most exciting fixture
